Clinical Pulmonary Infection Score (CPIS) Calculator

This calculator may be used to calculate the Clinical Pulmonary Infection Score (CPIS). The CPIS is used to assist in the clinical diagnosis of ventilator-associated pneumonia (VAP) by predicting which patients will benefit from obtaining pulmonary cultures. Use of the CPIS results in fewer missed VAP episodes and can also prevent unnecessary antibiotic administration due to treatment of colonized patients.


Score (check all that apply)
Temperature (Celsius) >36.5 and <38.4
>38.5 and <38.9
>39.0 or <36.5
White Blood Cell Count >4,000 and <11,000
<4,000 or >11,000
<4,000 or >11,000 AND band forms >50%
Tracheal Secretions None or scant
(*ARDS is defined as a PaO2/FiO2 <200, PAOP <18 mmHg, and acute bilateral infiltrates)
>240, ARDS* or pulmonary contusion
<240 and no ARDS*
Chest Radiograph No infiltrate
Diffuse (or patchy) infiltrate
Localized infiltrate

For further details on the diagnosis of Ventilator-Associated Pneumonia (VAP) and its treatment, review the evidence-based medicine guideline Diagnosis of Ventilator-Associated Pneumonia